CDSN and CSTF2T

Data Source:
BioGRID (two hybrid)

		CDSN	CSTF2T
Description		corneodesmosin	cleavage stimulation factor subunit 2 tau variant
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Plasma Membrane Cell-cell Junction Desmosome	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Homodimerization Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Corneocyte Desquamation Cell Adhesion Epidermis Development Keratinocyte Differentiation Skin Morphogenesis Cornification Cell-cell Adhesion Negative Regulation Of Cornification	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		Formation of the cornified envelope	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases		Hypotrichosis simplex of scalp
GWAS		Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Blood protein levels ( 28240269) Hematology traits ( 23263863) Hemoglobin levels ( 32327693) HIV-1 control ( 20041166) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Multiple myeloma ( 23955597) Schizophrenia ( 28991256) Takayasu arteritis ( 25604533) Ulcerative colitis ( 28067908) White blood cell count ( 20139978 21738480)	Interferon alpha levels in systemic lupus erythematosus ( 25338677) Logical memory (delayed recall) in normal cognition ( 29274321) Mammographic density (non-dense area) ( 25342443)
Interacting Genes		37 interacting genes: ASPH ATXN1L BAG6 BANP CCHCR1 CEP55 CSTF2 CSTF2T CTNNA3 DESI1 EIF3F ENKD1 EXOC8 FAM9B HGS HPCAL4 ITPRIPL1 KCNIP3 KLK7 LCN2 NCS1 NELFCD PARVG PLVAP PRKAB2 SGTA SGTB SMARCD1 TGM7 TRIM69 TSGA10 UBQLN1 UBQLN2 UBQLN4 UCHL5 VSNL1 ZDHHC17	23 interacting genes: AKAP8L ATP23 CDSN COL17A1 CPSF1 CTAG1A CTAG1B CTDSP1 FAM168B FOXI1 FOXJ2 GOLGA2 HGS LASP1 PKNOX2 SMYD3 SPAG8 STH TLE5 TOX2 UBQLN1 UBQLN2 UBQLN4
Entrez ID		1041	23283
HPRD ID		03998	09900
Ensembl ID		ENSG00000204539	ENSG00000177613
Uniprot IDs		G8JLG2 Q15517	Q9H0L4
PDB IDs
Enriched GO Terms of Interacting Partners?
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