HMG20A and OLIG3

Data Source:
BioGRID (two hybrid)

		HMG20A	OLIG3
Description		high mobility group 20A	oligodendrocyte transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spinal Cord Motor Neuron Cell Fate Specification Neuron Differentiation Spinal Cord Motor Neuron Migration
Pathways
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Celiac disease ( 22057235) Celiac disease and Rheumatoid arthritis ( 26546613) Cognitive decline rate in late mild cognitive impairment ( 26252872) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) Hodgkin's lymphoma ( 30194254) Multiple sclerosis ( 31604244 21833088) Primary biliary cholangitis ( 26394269) Rheumatoid arthritis ( 18794853 20453841 17982456) Rheumatoid arthritis (ACPA-positive) ( 24532676) Systemic lupus erythematosus ( 28714469) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Tonsillectomy ( 27182965 28928442)
Interacting Genes		58 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	29 interacting genes: AP1M1 ARID5A ATN1 BYSL CADPS CARD10 CYSRT1 HMG20A KRT86 KRTAP1-1 KRTAP10-8 KRTAP11-1 KRTAP19-2 KRTAP19-5 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-8 MDFI MFAP1 PLAGL2 PROP1 RUNX1 TCF12 TLE5 TRAF1 WWOX
Entrez ID		10363	167826
HPRD ID		16116	17662
Ensembl ID		ENSG00000140382	ENSG00000177468
Uniprot IDs		B4DMG1 Q9NP66	Q7RTU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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