HMG20A and RPP30

Data Source:
BioGRID (two hybrid, two hybrid)

		HMG20A	RPP30
Description		high mobility group 20A	ribonuclease P/MRP subunit p30
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	DNA Binding Protein Binding Identical Protein Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Negative Regulation Of Neuron Differentiation	TRNA 5'-leader Removal RRNA Processing TRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Hand grip strength ( 29691431) Hemoglobin A1c levels ( 29403010) Medication use (drugs used in diabetes) ( 31015401) Type 2 diabetes ( 21490949 22885922 24509480 30054458 22693455 21874001 30297969 32499647 30718926 28869590)	Economic and political preferences (time) ( 22566634) Metabolite levels ( 23823483)
Interacting Genes		58 interacting genes: ADD1 AGR2 BACH2 BRAP C9orf72 CCDC136 CCNK CEP95 CFAP53 DCTN4 DDIT4L DGCR6L DTNA DTNB FBXO7 FMNL1 FOXD4L1 GADD45GIP1 GPSM1 GTF2A1L HMG20B HPCAL1 KIFC3 KPNA2 KRT1 LMO1 LNX1 LURAP1 MAGOHB NTAQ1 NUTF2 OLIG3 PHF21A PIAS2 PICK1 PSMB1 PSORS1C2 PSTPIP1 PTH2R QARS1 RAD54L2 RBM7 RIN1 RPP30 RPRD1B RSPH9 RUSC1 SCNM1 SMAD4 SMYD1 SUOX SYTL4 TBC1D22B TCP11L1 TESC TRAF4 TRAPPC5 USHBP1	11 interacting genes: HMG20A MAST1 POP1 POP4 POP5 PTEN RNF32 RPP14 RPP21 RPP38 RPP40
Entrez ID		10363	10556
HPRD ID		16116	09359
Ensembl ID		ENSG00000140382	ENSG00000148688
Uniprot IDs		B4DMG1 Q9NP66	P78346
PDB IDs			6AHR 6AHU
Enriched GO Terms of Interacting Partners?
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