CDKN2D and SH3GLB1

Data Source:
BioGRID (two hybrid)

		CDKN2D	SH3GLB1
Description		cyclin dependent kinase inhibitor 2D	SH3 domain containing GRB2 like, endophilin B1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cyclin D2-CDK4 Complex	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Autophagic Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		63 interacting genes: APP BRCA1 BTG1 C1orf94 C5orf49 CCND3 CDK4 CDK6 CGGBP1 CTBP1 DDIT4L DMRTB1 DYNLT2B EIF4G1 FAM228A FAM86C1P FHL3 GATAD2B GLYR1 GORASP2 GSC2 HSD17B14 IKZF3 INCA1 KRT75 LNX1 LONRF1 LSM3 MEI4 MEOX2 MSS51 MTF2 NDUFB7 NIF3L1 NME4 NMI NR4A1 NR4A2 NR4A3 PICK1 PRDX5 PRIMPOL PSMA1 QKI REL RUFY4 SAXO1 SDCBP SH3GLB1 SH3GLB2 TBC1D17 TEX11 THAP1 TSG101 TSGA10IP UQCC2 VGLL1 YPEL3 ZBTB32 ZNF396 ZNF620 ZNF688 ZNF774	52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576
Entrez ID		1032	51100
HPRD ID		02957	15333
Ensembl ID		ENSG00000129355	ENSG00000097033
Uniprot IDs		A0A024R796 P55273	A0A087WW40 A0A140VJU5 Q9Y371
PDB IDs		1BD8 1BI8	6UP6 6UPN
Enriched GO Terms of Interacting Partners?
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