DNAJA2 and DNAJB1

Data Source:
BioGRID (pull down)

		DNAJA2	DNAJB1
Description		DnaJ heat shock protein family (Hsp40) member A2	DnaJ heat shock protein family (Hsp40) member B1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Postsynaptic Density Neuronal Cell Body Dendritic Spine Sperm Head Extracellular Exosome Glutamatergic Synapse
	Molecular Function	ATPase Activator Activity Protein Binding ATP Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	ATPase Activator Activity Transcription Corepressor Activity Protein Binding Hsp70 Protein Binding Protein Folding Chaperone Cadherin Binding Unfolded Protein Binding Chaperone Binding ATPase Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of ATPase Activity Protein Refolding	Negative Regulation Of Transcription By RNA Polymerase II Response To Unfolded Protein Forebrain Development Positive Regulation Of ATPase Activity Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Inclusion Body Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Cellular Response To Heat
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR)	Regulation of HSF1-mediated heat shock response HSP90 chaperone cycle for steroid hormone receptors (SHR) Attenuation phase HSF1-dependent transactivation MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Factor VII activity ( 30642921)	Adventurousness ( 30643258) General risk tolerance (MTAG) ( 30643258)
Interacting Genes		5 interacting genes: DNAJB1 DYNLT1 ERG HSPA1A PTEN	33 interacting genes: A2M AKT1 ANK2 APP BDKRB1 BRCA1 BRMS1 CENPE CYP2C8 DNAJA2 DNAJC3 ECSIT FANCA FANCC GLB1 HSF1 HSPA1A HSPA4 HSPA8 MAST1 NQO1 NRAS PEA15 PLEKHO1 PSEN2 PTGES3 SOD1 SPP1 STUB1 TERF1 TP53 TTLL12 ZFP36
Entrez ID		10294	3337
HPRD ID		07105	05198
Ensembl ID		ENSG00000069345	ENSG00000132002
Uniprot IDs		A0A024R6S1 O60884	P25685 Q6FHS4
PDB IDs			1HDJ 2QLD 3AGX 3AGY 3AGZ 4WB7 6BYR
Enriched GO Terms of Interacting Partners?
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