EIF1B and TRIM38

Data Source:
BioGRID (two hybrid)

		EIF1B	TRIM38
Description		eukaryotic translation initiation factor 1B	tripartite motif containing 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Eukaryotic 43S Preinitiation Complex	Cellular_component Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Ribosomal Small Subunit Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Translational Initiation Regulation Of Translational Initiation	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cardiac hypertrophy ( 21348951) Fish- and plant-related diet ( 32066663) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: ATXN1 DVL2 DVL3 PEX19 SPG21 TRIM38	30 interacting genes: ATXN1 BYSL EIF1B GMCL1 GORASP2 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 MTURN PIAS4 PSMA4 RFC5 RIPK1 RNF4 SDCBP STXBP1 TCEA2 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U ZNF764
Entrez ID		10289	10475
HPRD ID		17032	15555
Ensembl ID		ENSG00000114784	ENSG00000112343
Uniprot IDs		O60739 Q6FG85	A0A024QZY4 O00635
PDB IDs
Enriched GO Terms of Interacting Partners?
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