EFS and SH2D3C

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EFS	SH2D3C
Description		embryonal Fyn-associated substrate	SH2 domain containing 3C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Focal Adhesion	Cytoplasm Axon Ruffle Membrane
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization	JNK Cascade Small GTPase Mediated Signal Transduction Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS			Basophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		35 interacting genes: ABI2 AGXT APP BCAR1 BDKRB2 BLK CCDC187 CRK FYN GLMN GPANK1 LHX8 LYST MYOZ3 NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PIN1 PTK2 PTK2B PTPN12 SH2D3C SH3RF2 SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBASH3B UBC YES1 ZNF417	16 interacting genes: AR BCAR1 CARD11 EFS EGFR EPHB2 ERBB2 ERBB3 ERBB4 KIT MAPK1 MET NEDD9 PTK2B SNCAIP SRC
Entrez ID		10278	10044
HPRD ID		09932	05284
Ensembl ID		ENSG00000100842	ENSG00000095370
Uniprot IDs		O43281	B4DG32 Q8N5H7
PDB IDs			3T6G
Enriched GO Terms of Interacting Partners?
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