SH2D3C and EFS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SH2D3C	EFS
Description		SH2 domain containing 3C	embryonal Fyn-associated substrate
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon Ruffle Membrane	Cytoplasm Plasma Membrane Focal Adhesion
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	JNK Cascade Small GTPase Mediated Signal Transduction Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization
Pathways
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		16 interacting genes: AR BCAR1 CARD11 EFS EGFR EPHB2 ERBB2 ERBB3 ERBB4 KIT MAPK1 MET NEDD9 PTK2B SNCAIP SRC	35 interacting genes: ABI2 AGXT APP BCAR1 BDKRB2 BLK CCDC187 CRK FYN GLMN GPANK1 LHX8 LYST MYOZ3 NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PIN1 PTK2 PTK2B PTPN12 SH2D3C SH3RF2 SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBASH3B UBC YES1 ZNF417
Entrez ID		10044	10278
HPRD ID		05284	09932
Ensembl ID		ENSG00000095370	ENSG00000100842
Uniprot IDs		B4DG32 Q8N5H7	O43281
PDB IDs		3T6G
Enriched GO Terms of Interacting Partners?
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