MPHOSPH6 and DYNLRB1

Data Source:
HPRD (two hybrid)

		MPHOSPH6	DYNLRB1
Description		M-phase phosphoprotein 6	dynein light chain roadblock-type 1
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GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytosol	Cytoplasm Centrosome Cytoplasmic Dynein Complex Microtubule Cilium Membrane Ciliary Tip
	Molecular Function	RNA Binding Protein Binding	Microtubule Motor Activity Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Maturation Of 5.8S RRNA RRNA Processing	Microtubule-based Movement Visual Behavior Intraciliary Transport Involved In Cilium Assembly
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Intraflagellar transport
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Nevus count or cutaneous melanoma ( 32341527) Obesity-related traits ( 23251661) Seasonality and depression ( 30217971)	Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30224653)
Interacting Genes		32 interacting genes: AATF APLP1 ARHGAP18 DNM2 DYNLRB1 EIF3G ERG28 EXOSC1 EXOSC10 EXOSC3 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL GDF9 HSPB1 KNSTRN LRIF1 MTREX NUPR1 PARN RBM48 RPS20 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	9 interacting genes: CPEB1 CRCP DYNC1I1 DYNC1I2 HSPH1 MAGEA2 MAGEA2B MPHOSPH6 PALS2
Entrez ID		10200	83658
HPRD ID		16111	06203
Ensembl ID		ENSG00000135698	ENSG00000125971
Uniprot IDs		H3BNT4 Q99547	B4DFR2 Q9NP97
PDB IDs		6D6Q 6D6R 6H25	1Z09 2B95 2E8J 2HZ5 6F1T 6F1Z 6F38 6F3A 6RLB 6SC2
Enriched GO Terms of Interacting Partners?
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