PRMT3 and PABPN1

Data Source:
HPRD (in vitro)

		PRMT3	PABPN1
Description		protein arginine methyltransferase 3	poly(A) binding protein nuclear 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex
	Molecular Function	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding	RNA Binding Protein Binding RNA Polymerase Binding
	Biological Process	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation	MAPK Cascade MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity
Pathways		RMTs methylate histone arginines Protein methylation	Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs		S-adenosyl-L-homocysteine
Diseases			Oculopharyngeal muscular dystrophy (OPMD)
GWAS		Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)	Body mass index ( 26865924) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 RPS2 STAT1 TSC22D2	13 interacting genes: CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ
Entrez ID		10196	8106
HPRD ID		11934	03787
Ensembl ID		ENSG00000185238	ENSG00000100836
Uniprot IDs		O60678 Q8WUV3	Q86U42
PDB IDs		2FYT 3SMQ 4HSG 4QQN 4RYL	3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?
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