TRIM10 and TRIM44

Data Source:
BioGRID (two hybrid)

		TRIM10	TRIM44
Description		tripartite motif containing 10	tripartite motif containing 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Biological_process Regulation Of Gene Expression Protein Ubiquitination Erythrocyte Differentiation Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell	Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Defense Response To Virus By Host Regulation Of Gene Expression Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated Protein Stabilization Negative Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Neuroticism ( 29255261) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Metabolite levels ( 23823483) Photic sneeze reflex ( 27182965) Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103)
Interacting Genes		17 interacting genes: GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620	9 interacting genes: APP FBXO7 HINFP MORN4 NEDD4 PBX3 PICK1 TRIM10 TRIM69
Entrez ID		10107	54765
HPRD ID		05752	15561
Ensembl ID		ENSG00000204613	ENSG00000166326
Uniprot IDs		A0A1U9X8M5 Q9UDY6	Q96DX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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