TRIM10 and TRIM35

Data Source:
BioGRID (two hybrid)

		TRIM10	TRIM35
Description		tripartite motif containing 10	tripartite motif containing 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Biological_process Regulation Of Gene Expression Protein Ubiquitination Erythrocyte Differentiation Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell
Pathways		Interferon gamma signaling	Interferon gamma signaling
Drugs
Diseases
GWAS		Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Neuroticism ( 29255261) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		17 interacting genes: GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620	49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410
Entrez ID		10107	23087
HPRD ID		05752	15553
Ensembl ID		ENSG00000204613	ENSG00000104228
Uniprot IDs		A0A1U9X8M5 Q9UDY6	E5RGB3 Q9UPQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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