STRIT1 and KCNK5

Data Source:
BioGRID (two hybrid)

		STRIT1	KCNK5
Description		small transmembrane regulator of ion transport 1	potassium two pore domain channel subfamily K member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Sarcoplasmic Reticulum Membrane	Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity	Voltage-gated Ion Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Leak Channel Activity
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Regulation Of Catalytic Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Potassium Ion Transport Excretion Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane
Pathways			Phase 4 - resting membrane potential
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Coronary artery disease ( 32469254 29212778 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Eating disorders ( 23568457) HDL cholesterol levels ( 32203549) Kidney stones ( 31729369) Migraine ( 27322543) Myocardial infarction ( 26343387) Obesity-related traits ( 23251661) Social communication problems ( 24564958) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Urolithiasis ( 30975718)
Interacting Genes		45 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R F11R FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35C2 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	29 interacting genes: ADIPOQ AGTRAP APP AQP1 ATP5PF BNIP2 CMTM5 COMT CYB5B FRAT1 GJB2 IGFBP5 LHFPL5 MAN2B2 ORMDL3 SLC66A2 SMCO4 STRIT1 TM4SF4 TMEM128 TMEM14A TMEM176A TMEM218 TMEM54 TMEM60 TNFRSF10C TSPAN33 VAMP3 YIPF6
Entrez ID		100507537	8645
HPRD ID			04604
Ensembl ID		ENSG00000240045	ENSG00000164626
Uniprot IDs			A0A024RD32 A0A0B6VPR3 O95279
PDB IDs
Enriched GO Terms of Interacting Partners?
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