STRIT1 and EDA2R

Data Source:
BioGRID (two hybrid)

		STRIT1	EDA2R
Description		small transmembrane regulator of ion transport 1	ectodysplasin A2 receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Sarcoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity	Tumor Necrosis Factor-activated Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Regulation Of Catalytic Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Multicellular Organism Development Epidermis Development Ectodermal Cell Differentiation Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS			Balding ( 26926045) Male-pattern baldness ( 27182965 22032556 28196072)
Interacting Genes		45 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R F11R FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35C2 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	16 interacting genes: AGR3 ATP6V0C C1QB CASP8 CEBPE EDA FADD GIMAP5 JAGN1 NKG7 PLP1 SGTA STRIT1 TMEM262 TRAF3 TRAF6
Entrez ID		100507537	60401
HPRD ID			02230
Ensembl ID		ENSG00000240045	ENSG00000131080
Uniprot IDs			B2RBZ9 B4DQY6 Q9HAV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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