TOM1 and DNAL4

Data Source:
BioGRID (biochemical)

		TOM1	DNAL4
Description		target of myb1 membrane trafficking protein	dynein axonemal light chain 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex
	Molecular Function	Protein Binding Clathrin Binding	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Endocytosis Signal Transduction Protein Transport Endosomal Transport Neutrophil Degranulation	Microtubule-based Movement Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed
Pathways		Neutrophil degranulation	Retrograde neurotrophin signalling
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: APP CLTC DAZAP2 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 PILRA PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	16 interacting genes: CAMK2D CHIC2 DYNLL1 DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 KRTAP12-3 KRTAP9-8 NFATC2IP NOTCH2NLA NTAQ1 NUDT22 SCTR TRIM54
Entrez ID		10043	10126
HPRD ID		05265	13239
Ensembl ID		ENSG00000100284	ENSG00000100246
Uniprot IDs		B3KUF5 O60784	O96015
PDB IDs		1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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