TMEM239 and CXCL16

Data Source:
BioGRID (two hybrid, two hybrid)

		TMEM239	CXCL16
Description		transmembrane protein 239	C-X-C motif chemokine ligand 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Chemokine Activity
	Biological Process		Receptor-mediated Endocytosis Chemotaxis G Protein-coupled Receptor Signaling Pathway T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)	Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		67 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MFSD14B MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35C2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5	63 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC16A2 SLC18A1 SLC39A1 SPN SSMEM1 STX1A TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12
Entrez ID		100288797	58191
HPRD ID			16103
Ensembl ID		ENSG00000198326	ENSG00000161921
Uniprot IDs		Q8WW34	A0A6I8PIU0 Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?
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