TMEM239 and SLC34A2

Data Source:
BioGRID (two hybrid)

		TMEM239	SLC34A2
Description		transmembrane protein 239	solute carrier family 34 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Brush Border Integral Component Of Membrane Apical Plasma Membrane Brush Border Membrane Vesicle
	Molecular Function	Protein Binding	Sodium:phosphate Symporter Activity Sodium Ion Binding Phosphate Ion Binding
	Biological Process		In Utero Embryonic Development Phosphate Ion Transport Cellular Phosphate Ion Homeostasis Sodium Ion Transmembrane Transport Response To Estrogen Cellular Protein Metabolic Process Sodium-dependent Phosphate Transport
Pathways			Type II Na+/Pi cotransporters Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) Surfactant metabolism Defective SLC34A2 causes PALM
Drugs
Diseases			Non-small cell lung cancer
GWAS		Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)	Metabolite levels ( 23823483)
Interacting Genes		67 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MFSD14B MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35C2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5	19 interacting genes: AIG1 ERG28 FXYD6-FXYD2 GUCA2A JAGN1 LHFPL5 PLN PNLIPRP1 RTP2 SLC30A3 SLC35A1 SLC39A7 STRIT1 TEX264 TMEM128 TMEM239 TMEM42 TRARG1 TSPO2
Entrez ID		100288797	10568
HPRD ID			07251
Ensembl ID		ENSG00000198326	ENSG00000157765
Uniprot IDs		Q8WW34	O95436
PDB IDs
Enriched GO Terms of Interacting Partners?
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