SYCE1L and CENPP

Data Source:
BioGRID (two hybrid)

		SYCE1L	CENPP
Description		synaptonemal complex central element protein 1 like	centromere protein P
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Intermediate Filament Cytoskeleton	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function		Protein Binding
	Biological Process	Synaptonemal Complex Assembly	CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)	Blood protein levels ( 29875488) End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528)
Interacting Genes		36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526	27 interacting genes: ATP6V0D2 BACH2 C2orf88 CCDC33 CCDC85B CENPO CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765
Entrez ID		100130958	401541
HPRD ID			17989
Ensembl ID		ENSG00000205078	ENSG00000188312
Uniprot IDs		A8MT33	Q6IPU0 Q7Z672
PDB IDs
Enriched GO Terms of Interacting Partners?
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