SYCE1L and KCNIP2

Data Source:
BioGRID (two hybrid)

		SYCE1L	KCNIP2
Description		synaptonemal complex central element protein 1 like	potassium voltage-gated channel interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Intermediate Filament Cytoskeleton	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Potassium Channel Complex Synapse
	Molecular Function		A-type (transient Outward) Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Ion Channel Binding ER Retention Sequence Binding Protein N-terminus Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Synaptonemal Complex Assembly	Detection Of Calcium Ion Potassium Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Regulation Of Heart Contraction Clustering Of Voltage-gated Potassium Channels Cardiac Conduction Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Voltage-gated Potassium Channel Activity
Pathways			Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)	Raw vegetable consumption ( 32066663)
Interacting Genes		36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526	5 interacting genes: GOLGA7 KCND2 KCND3 KCNIP1 SYCE1L
Entrez ID		100130958	30819
HPRD ID			06880
Ensembl ID		ENSG00000205078	ENSG00000120049
Uniprot IDs		A8MT33	A0A2R8Y6D7 B3KSZ5 Q9NS61
PDB IDs
Enriched GO Terms of Interacting Partners?
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