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LRRK1
Description
leucine rich repeat kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Cytosol
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Serine/threonine Phosphatase Activity
Protein Binding
ATP Binding
GTP Binding
Identical Protein Binding
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Protein Phosphorylation
Protein Dephosphorylation
Signal Transduction
Osteoclast Development
Bone Resorption
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Central corneal thickness (
32528159
28171582
31798171
29760442
)
Corneal structure (
23291589
)
Height (
28552196
)
Novel Interacting Genes
2 novel interacting genes:
SELENOS
TM2D3
Interacting Genes
51 interacting genes:
ABL1
BAG1
BAG2
BAG3
BAG5
BLOC1S5
C11orf52
CBLB
CCL21
CD2BP2
CDC42EP3
CHGB
CKAP2
CLVS1
CPLX3
CWC15
ECHS1
EGFR
ENKUR
EPHA8
FAM184A
FBXL14
FGFR2
FLT4
FOXP1
GAK
GNAZ
GPBP1L1
ITCH
KIF20A
MATK
MTG1
NEK1
NUDT16L1
ODF2
PAK6
PDCD4
PLK1
POLR2M
RAB29
RET
SCEL
SH2D2A
SNX21
SNX9
STUB1
TCF25
TEC
TEX33
TIRAP
VGLL4
Entrez ID
79705
HPRD ID
14319
Ensembl ID
ENSG00000154237
Uniprot IDs
Q38SD2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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