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SAA1
Description
serum amyloid A1
Image
GO Annotations
Cellular Component
Extracellular Region
Cytoplasmic Microtubule
High-density Lipoprotein Particle
Extracellular Exosome
Endocytic Vesicle Lumen
Molecular Function
G Protein-coupled Receptor Binding
Heparin Binding
Biological Process
Activation Of MAPK Activity
Positive Regulation Of Cytokine Production
Receptor-mediated Endocytosis
Acute-phase Response
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cytokine-mediated Signaling Pathway
Platelet Activation
Neutrophil Chemotaxis
Positive Regulation Of Interleukin-1 Production
Cellular Protein Metabolic Process
Innate Immune Response
Positive Regulation Of Cell Adhesion
Macrophage Chemotaxis
Lymphocyte Chemotaxis
Regulation Of Protein Secretion
Negative Regulation Of Inflammatory Response
Pathways
Scavenging by Class B Receptors
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Interleukin-4 and Interleukin-13 signaling
Advanced glycosylation endproduct receptor signaling
Advanced glycosylation endproduct receptor signaling
TRAF6 mediated NF-kB activation
Amyloid fiber formation
Drugs
Diseases
GWAS
Amyloid A serum levels (
21124955
)
Blood protein levels (
30072576
29875488
28240269
)
Rosacea symptom severity (
29771307
)
Novel Interacting Genes
1 novel interacting genes:
GNG5
Interacting Genes
9 interacting genes:
COL4A1
COL4A2
COL4A3
COL4A4
FPR1
GLP1R
LAMA1
SELENOS
VKORC1
Entrez ID
6288
HPRD ID
00097
Ensembl ID
ENSG00000173432
Uniprot IDs
P0DJI8
PDB IDs
4IP8
4IP9
6MST
Enriched GO Terms of Interacting Partners
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