FERMT1

Description		FERM domain containing kindlin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Focal Adhesion Cell Junction Cell-substrate Junction Ruffle Membrane Cell Periphery
	Molecular Function	Integrin Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Integrin Activation Positive Regulation Of Cell Adhesion Mediated By Integrin Negative Regulation Of Protein Import Into Nucleus Keratinocyte Proliferation Keratinocyte Migration Negative Regulation Of Timing Of Anagen Positive Regulation Of Transforming Growth Factor Beta Production Basement Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Establishment Of Epithelial Cell Polarity Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases		Kindler syndrome
GWAS		Abdominal aortic aneurysm ( 27899403) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lung function (low FEV1 vs high FEV1) ( 26423011) Retinal detachment or retinal break ( 31816047) Smooth-surface caries ( 24556642) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		4 interacting genes: ILK ITGB1 PARVA SRPK1
Entrez ID		55612
HPRD ID		06388
Ensembl ID		ENSG00000101311
Uniprot IDs		Q49AC8 Q54A15 Q9BQL6
PDB IDs
Enriched GO Terms of Interacting Partners?
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