MYO5B

Description		myosin VB
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GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Myosin Complex Cytoplasmic Vesicle Membrane Vesicle Protein-containing Complex Apical Cortex Recycling Endosome Extracellular Exosome
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Actin-dependent ATPase Activity Small GTPase Binding Actin Filament Binding
	Biological Process	Renal Water Homeostasis Actin Filament Organization Protein Transport Vesicle-mediated Transport Endosomal Transport Vesicle Transport Along Actin Filament
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549 29084231) HDL cholesterol levels ( 32203549) Large HDL particle concentration ( 29084231) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Multiple sclerosis ( 31604244) Myopia ( 27182965) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Refractive error ( 32231278) Resistant hypertension ( 31545351) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231)
Interacting Genes		20 interacting genes: AMOTL2 BNIP2 COIL CXCR2 EFHC2 FAM214B GMCL1 KIAA1549 MEI4 MEOX2 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SMAD3 TCF4 TRIM3 TRIM54 ZNHIT1
Entrez ID		4645
HPRD ID		07582
Ensembl ID		ENSG00000167306
Uniprot IDs		Q7Z7A5 Q9ULV0
PDB IDs		4J5M 4LNZ 4LWZ 4LX0
Enriched GO Terms of Interacting Partners?
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