SPEN

Description		spen family transcriptional repressor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Repressor Complex Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Factor Binding Nucleic Acid Binding DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome Notch Signaling Pathway Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurogenesis
Pathways
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Heel bone mineral density ( 28869591) Hemoglobin levels ( 32327693)
Interacting Genes		22 interacting genes: ATXN1 CLK1 CTBP1 DLX5 HDAC1 HDAC2 MBD3 MSX2 MTA2 NCOR1 NCOR2 PPARD RARA RBBP4 RBPJ RIDA RUNX1 RUNX1T1 SERTAD1 SOX9 SRPK2 UBE2L6
Entrez ID		23013
HPRD ID		10230
Ensembl ID		ENSG00000065526
Uniprot IDs		Q96T58
PDB IDs		1OW1 2RT5 4P6Q
Enriched GO Terms of Interacting Partners?
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