ULK2 and DIXDC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ULK2	DIXDC1
Description		unc-51 like autophagy activating kinase 2	DIX domain containing 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Vesicle Membrane Phagophore Assembly Site Membrane	Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Actin Binding Protein Binding Protein Domain Specific Binding Gamma-tubulin Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Signal Transduction Peptidyl-serine Phosphorylation Piecemeal Microautophagy Of The Nucleus Response To Starvation Late Nucleophagy Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension Reticulophagy Positive Regulation By Symbiont Of Host Autophagy	Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Wnt Signaling Pathway Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Neuron Differentiation Canonical Wnt Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization
Pathways
Drugs		Fostamatinib
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Smoking initiation ( 33082346) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		16 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 RAI1 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32	8 interacting genes: APP ATXN1 AXIN1 CDC5L MAP3K4 NDEL1 ULK2 ZDHHC17
Entrez ID		9706	85458
HPRD ID		10556	16804
Ensembl ID		ENSG00000083290	ENSG00000150764
Uniprot IDs		Q8IYT8	Q155Q3
PDB IDs		6QAT 6QAU 6QAV 6YID	3PZ7
Enriched GO Terms of Interacting Partners?
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