DIXDC1 and ULK2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		DIXDC1	ULK2
Description		DIX domain containing 1	unc-51 like autophagy activating kinase 2
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Focal Adhesion	Cytoplasm Cytoplasmic Vesicle Membrane Phagophore Assembly Site Membrane
	Molecular Function	Actin Binding Protein Binding Protein Domain Specific Binding Gamma-tubulin Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of Wnt Signaling Pathway Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Neuron Differentiation Canonical Wnt Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Signal Transduction Peptidyl-serine Phosphorylation Piecemeal Microautophagy Of The Nucleus Response To Starvation Late Nucleophagy Protein Autophosphorylation Negative Regulation Of Collateral Sprouting Axon Extension Reticulophagy Positive Regulation By Symbiont Of Host Autophagy
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Smoking initiation ( 33082346) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: APP ATXN1 AXIN1 CDC5L MAP3K4 NDEL1 ULK2 ZDHHC17	16 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 RAI1 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32
Entrez ID		85458	9706
HPRD ID		16804	10556
Ensembl ID		ENSG00000150764	ENSG00000083290
Uniprot IDs		Q155Q3	Q8IYT8
PDB IDs		3PZ7	6QAT 6QAU 6QAV 6YID
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?