CLOCK and SIRT1

  • Number of citations of the paper that reports this interaction (PubMedID 18662547)
  • 535

CLOCK

SIRT1

Description clock circadian regulator sirtuin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body shape index ( 34021172)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Coronary artery disease ( 33020668)
  • Cortical surface area (MOSTest) ( 32665545)
  • Height ( 25282103)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Neutrophil percentage of white cells ( 32888494)
  • Personality dimensions ( 18957941)
  • Subcortical volume (MOSTest) ( 32665545)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 27 interacting genes: ARNTL ARNTL2 BHLHE41 CEP135 CRY1 CRY2 CSNK1E CSNK2B DBP DELEC1 EP300 KAT2B NPAS2 PER2 PER3 PPP1CA PPP1CB PPP1CC PPP2R1B PPP2R5D PPP2R5E RARA RHOA RORB RORC RXRA SIRT1 65 interacting genes: AFP AKT1 AR ARNTL BAZ1B BCL11A BHLHE41 BRIP1 CDK6 CENATAC CHFR CLOCK CSNK2B CTTN E2F1 EP300 ESRRA EZH2 FOS FOXM1 FOXO1 FOXO3 GAPDH H1-5 H3C1 HES1 HEY2 HIC1 HIPK2 HNF4A HOXB9 MAPK8 MPHOSPH8 MYCN NBN NDN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARG PPARGC1A PRMT1 PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SMURF2 SNW1 STK11 STK4 SUMO2 TP53 TP73 TRIM28 UBE2I USP22 VDR
Entrez ID 9575 23411
HPRD ID 03508 08381
Ensembl ID ENSG00000134852 ENSG00000096717
Uniprot IDs O15516 Q3ZCT4 Q53EU0 A0A024QZQ1 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 4H10 6QPJ 4I5I 4IF6 4IG9 4KXQ 4ZZH 4ZZI 4ZZJ 5BTR
Enriched GO Terms of Interacting Partners?
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