VPS26A and DEDD

		VPS26A	DEDD
Description		VPS26, retromer complex component A	death effector domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Vesicle Tubular Endosome	Nucleolus Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Macroautophagy Endocytic Recycling Retrograde Transport, Endosome To Golgi	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Type 2 diabetes ( 21874001 30718926)
Interacting Genes		5 interacting genes: DEDD MORF4L1 RAB7A VPS35 ZSCAN12	24 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 IRF9 KRT18 KRT8 MPZ NR1I3 PRRC2C SDHC SHMT1 SLC19A2 SMAD3 UAP1 VPS26A
Entrez ID		9559	9191
HPRD ID		08385	06022
Ensembl ID		ENSG00000122958	ENSG00000158796
Uniprot IDs		B4DLT1 O75436	B1AQP5 O75618
PDB IDs		2FAU 5F0J 5F0L 5F0M 5F0P 7BLO
Enriched GO Terms of Interacting Partners?
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