DEDD and VPS26A

		DEDD	VPS26A
Description		death effector domain containing	VPS26, retromer complex component A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm	Lysosome Endosome Early Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Vesicle Tubular Endosome
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I	Intracellular Protein Transport Regulation Of Macroautophagy Endocytic Recycling Retrograde Transport, Endosome To Golgi
Pathways			WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS			Body size at age 10 ( 32376654) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Type 2 diabetes ( 21874001 30718926)
Interacting Genes		24 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 IRF9 KRT18 KRT8 MPZ NR1I3 PRRC2C SDHC SHMT1 SLC19A2 SMAD3 UAP1 VPS26A	5 interacting genes: DEDD MORF4L1 RAB7A VPS35 ZSCAN12
Entrez ID		9191	9559
HPRD ID		06022	08385
Ensembl ID		ENSG00000158796	ENSG00000122958
Uniprot IDs		B1AQP5 O75618	B4DLT1 O75436
PDB IDs			2FAU 5F0J 5F0L 5F0M 5F0P 7BLO
Enriched GO Terms of Interacting Partners?
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