VPS26A and VPS35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VPS26A	VPS35
Description		VPS26, retromer complex component A	VPS35 retromer complex component
Image
GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Vesicle Tubular Endosome	Mitochondrion Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Extracellular Exosome Tubular Endosome Mitochondrion-derived Vesicle
	Molecular Function	Protein Binding	Protein Binding D1 Dopamine Receptor Binding
	Biological Process	Intracellular Protein Transport Regulation Of Macroautophagy Endocytic Recycling Retrograde Transport, Endosome To Golgi	Intracellular Protein Transport Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Wnt Signaling Pathway Regulation Of Macroautophagy Regulation Of Protein Stability Regulation Of Cellular Protein Metabolic Process Endocytic Recycling Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Mitochondrial Fragmentation Involved In Apoptotic Process Transcytosis Negative Regulation Of Inflammatory Response Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Transport Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Negative Regulation Of Neuron Death Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Dendritic Spine Maintenance Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Presynapse Assembly Regulation Of Terminal Button Organization
Pathways		WNT ligand biogenesis and trafficking	WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Type 2 diabetes ( 21874001 30718926)
Interacting Genes		5 interacting genes: DEDD MORF4L1 RAB7A VPS35 ZSCAN12	15 interacting genes: APP DRD1 GNL1 LINC01554 MTNR1B PRPF19 SLC11A2 SNX1 SNX3 VEGFA VPS26A VPS26B VPS29 YBX1 ZNF512B
Entrez ID		9559	55737
HPRD ID		08385	06085
Ensembl ID		ENSG00000122958	ENSG00000069329
Uniprot IDs		B4DLT1 O75436	Q96QK1
PDB IDs		2FAU 5F0J 5F0L 5F0M 5F0P 7BLO	2R17 5F0J 5F0K 5F0L 5F0M 5F0P 5OSH 5OSI 7BLN 7BLO
Enriched GO Terms of Interacting Partners?
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