TMEM203 and CD3G

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM203	CD3G
Description		transmembrane protein 203	CD3g molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Alpha-beta T Cell Receptor Complex
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding
	Biological Process	Cellular Calcium Ion Homeostasis Spermatogenesis	Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport T Cell Activation Positive Thymic T Cell Selection Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs			Muromonab
Diseases
GWAS
Interacting Genes		39 interacting genes: ANK1 AQP6 ATP6AP2 CD3G CNR2 CPLX4 CREB3 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 HSD17B11 HSD17B13 KCNJ6 LMNA LY6G6C MANBAL MFSD5 MMD PDZK1IP1 RETREG3 RMDN3 RNASEK SLC10A6 SLC18A1 SSMEM1 STOM STX4 TIMMDC1 TMEM14B TMEM234 TMEM31 TMEM52B TMEM60 TMEM86B TMX2	15 interacting genes: CD3D CD3E DRD2 EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD
Entrez ID		94107	917
HPRD ID		17496	07037
Ensembl ID		ENSG00000187713	ENSG00000160654
Uniprot IDs		Q969S6	B0YIY5 P09693
PDB IDs			1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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