CD3G and TMEM262

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CD3G	TMEM262
Description		CD3g molecule	transmembrane protein 262
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Alpha-beta T Cell Receptor Complex	Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport T Cell Activation Positive Thymic T Cell Selection Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs		Muromonab
Diseases
GWAS			Serum uric acid levels ( 32514006)
Interacting Genes		15 interacting genes: CD3D CD3E DRD2 EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD	14 interacting genes: AQP6 CD3G CD79A EDA2R EMP1 FFAR2 GPR42 KLRC1 MANBAL PCNX3 PSCA SHISAL1 SLC10A6 UPK1B
Entrez ID		917	100130348
HPRD ID		07037
Ensembl ID		ENSG00000160654	ENSG00000187066
Uniprot IDs		B0YIY5 P09693	E9PQX1
PDB IDs		1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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