CD3G and TMEM203

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CD3G	TMEM203
Description		CD3g molecule	transmembrane protein 203
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane Alpha-beta T Cell Receptor Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Complex Adaptor Activity T Cell Receptor Binding Identical Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Establishment Or Maintenance Of Cell Polarity Cell Surface Receptor Signaling Pathway Protein Transport T Cell Activation Positive Thymic T Cell Selection Protein-containing Complex Assembly Regulation Of Lymphocyte Apoptotic Process	Cellular Calcium Ion Homeostasis Spermatogenesis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules FCGR activation FCGR activation Regulation of actin dynamics for phagocytic cup formation Role of phospholipids in phagocytosis PD-1 signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis FCGR3A-mediated IL10 synthesis FCGR3A-mediated phagocytosis
Drugs		Muromonab
Diseases
GWAS
Interacting Genes		15 interacting genes: CD3D CD3E DRD2 EMP1 KTN1 LAT MAL PMP22 TMEM19 TMEM203 TMEM262 TMEM54 TRA TRB TRD	39 interacting genes: ANK1 AQP6 ATP6AP2 CD3G CNR2 CPLX4 CREB3 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 HSD17B11 HSD17B13 KCNJ6 LMNA LY6G6C MANBAL MFSD5 MMD PDZK1IP1 RETREG3 RMDN3 RNASEK SLC10A6 SLC18A1 SSMEM1 STOM STX4 TIMMDC1 TMEM14B TMEM234 TMEM31 TMEM52B TMEM60 TMEM86B TMX2
Entrez ID		917	94107
HPRD ID		07037	17496
Ensembl ID		ENSG00000160654	ENSG00000187713
Uniprot IDs		B0YIY5 P09693	Q969S6
PDB IDs		1SY6 6JXR
Enriched GO Terms of Interacting Partners?
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