ARHGEF1 and RAP1A

  • Number of citations of the paper that reports this interaction (PubMedID 12581858)
  • 20
  • Data Source:
  • BioGRID (enzymatic study)

ARHGEF1

RAP1A

Description Rho guanine nucleotide exchange factor 1 RAP1A, member of RAS oncogene family
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Crohn's disease ( 30500874 32581322)
  • High altitude adaptation ( 28373541)
  • Lymphocyte counts ( 32888494)
  • Osteoporosis-related phenotypes ( 20548944)
Interacting Genes 11 interacting genes: ATR CD44 CNKSR1 CSNK1E GNA13 HRAS PRKCA RAP1A RHOA SREBF2 TCF4 43 interacting genes: AFDN APBB1IP ARHGEF1 BIN1 BMX BRAF ELOA FADD FAF1 FAS GABARAPL2 GANAB HDAC1 HSPA1A HSPA4 KRIT1 MTNR1A NTRK1 PDE6D PPP2R1A PRKACA RABAC1 RAF1 RALGDS RAP1GAP RAP1GDS1 RAPGEF1 RAPGEF2 RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASA1 RASA3 RASGRP2 RASGRP4 RASIP1 RGL4 RGS14 RUNDC3A SMARCA2 SMARCA4 TNFRSF10C
Entrez ID 9138 5906
HPRD ID 03511 01545
Ensembl ID ENSG00000076928 ENSG00000116473
Uniprot IDs A0A024R0R1 Q92888 A8KAH9 P62834
PDB IDs 1IAP 1SHZ 3AB3 3ODO 3ODW 3ODX 3P6A 1C1Y 1GUA 3KUC 4KVG
Enriched GO Terms of Interacting Partners?
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