CLDN2 and BTN3A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDN2	BTN3A2
Description		claudin 2	butyrophilin subfamily 3 member A2
Image
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly	Regulation Of Cytokine Production T Cell Mediated Immunity Positive Regulation Of Interferon-gamma Production T Cell Receptor Signaling Pathway
Pathways		Tight junction interactions	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)	Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Epstein-Barr virus VCA p18 antibody levels ( 33204752) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference ( 31453325) Hip circumference adjusted for BMI ( 34021172) Hip circumference variance ( 31453325) Liver iron content ( 34128465) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Schizophrenia ( 19571809) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Walking pace ( 33128006) Weight ( 28552196)
Interacting Genes		29 interacting genes: ADAM33 BTN3A2 CLEC2D CSGALNACT2 CXCL9 CYSRT1 EMP3 FAM209A GRM2 IGFBP5 IL27RA KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP4-12 LAT LNX1 LPAR3 MTDH NOTCH2NLA PIAS2 PLP1 TEX264 TJP1 TJP2 TMEM218 UBE2I WNK4	1 interacting genes: CLDN2
Entrez ID		9075	11118
HPRD ID		06471	12547
Ensembl ID		ENSG00000165376	ENSG00000186470
Uniprot IDs		P57739	A8K4B5 P78410
PDB IDs		4YYX	4F8Q
Enriched GO Terms of Interacting Partners?
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