CLDN2 and PLP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLDN2	PLP1
Description		claudin 2	proteolipid protein 1
Image
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane	Plasma Membrane Integrin Alphav-beta3 Complex Myelin Sheath Synapse
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath Protein-containing Complex Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly	Inflammatory Response Chemical Synaptic Transmission Axon Ensheathment Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Positive Regulation Of Cell Migration Neuron Projection Development Long-chain Fatty Acid Biosynthetic Process Axon Development AMPA Selective Glutamate Receptor Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transport
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)
Interacting Genes		29 interacting genes: ADAM33 BTN3A2 CLEC2D CSGALNACT2 CXCL9 CYSRT1 EMP3 FAM209A GRM2 IGFBP5 IL27RA KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP4-12 LAT LNX1 LPAR3 MTDH NOTCH2NLA PIAS2 PLP1 TEX264 TJP1 TJP2 TMEM218 UBE2I WNK4	87 interacting genes: ADGRG3 AKT1 AQP10 AQP6 ARL13B BCL2L13 BIK CALN1 CALR CANX CD40 CD74 CDIPT CLDN2 CLDN20 CLEC2D CLN8 CREB3 CREB3L1 CYBC1 DCT DYSF EDA2R ELOVL4 ERGIC3 FAM209A FCRL2 FFAR2 FNDC9 GAST GLA GPR42 GPR61 HAS3 HTR2C IER3IP1 IFITM3 ITGAV JAGN1 JPH1 KLRC1 LEPROTL1 LEUTX LHFPL5 LMNA MAG MBP MFF MGST3 MS4A3 MS4A4A MTIF3 MUC1 MYADM NRG1 PI16 PIGP PTPRN RELL2 RMDN3 RNF24 SLC10A6 SLC16A2 SLC18A1 SLC1A5 SLC26A6 SLC35E2A SLC35E3 SLC41A3 SMIM3 SPNS3 STX1A STX4 SUSD3 TMEM106C TMEM14B TMEM182 TMEM242 TMEM243 TMEM254 TMEM31 TMEM45B TMEM52B TMEM97 TMPRSS2 UPK2 VAT1
Entrez ID		9075	5354
HPRD ID		06471	02321
Ensembl ID		ENSG00000165376	ENSG00000123560
Uniprot IDs		P57739	A0A0S2Z4D4 A8K9L3 B4DI30 P60201
PDB IDs		4YYX	2XPG
Enriched GO Terms of Interacting Partners?
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