BTN3A2 and CLDN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BTN3A2	CLDN2
Description		butyrophilin subfamily 3 member A2	claudin 2
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cytokine Production T Cell Mediated Immunity Positive Regulation Of Interferon-gamma Production T Cell Receptor Signaling Pathway	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways		Butyrophilin (BTN) family interactions	Tight junction interactions
Drugs
Diseases
GWAS		Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Epstein-Barr virus VCA p18 antibody levels ( 33204752) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Hip circumference ( 31453325) Hip circumference adjusted for BMI ( 34021172) Hip circumference variance ( 31453325) Liver iron content ( 34128465) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Schizophrenia ( 19571809) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Walking pace ( 33128006) Weight ( 28552196)	Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)
Interacting Genes		1 interacting genes: CLDN2	29 interacting genes: ADAM33 BTN3A2 CLEC2D CSGALNACT2 CXCL9 CYSRT1 EMP3 FAM209A GRM2 IGFBP5 IL27RA KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP4-12 LAT LNX1 LPAR3 MTDH NOTCH2NLA PIAS2 PLP1 TEX264 TJP1 TJP2 TMEM218 UBE2I WNK4
Entrez ID		11118	9075
HPRD ID		12547	06471
Ensembl ID		ENSG00000186470	ENSG00000165376
Uniprot IDs		A8K4B5 P78410	P57739
PDB IDs		4F8Q	4YYX
Enriched GO Terms of Interacting Partners?
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