PIAS2 and SOX5

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

PIAS2

SOX5

Description protein inhibitor of activated STAT 2 SRY-box transcription factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Age at first sexual intercourse ( 34211149)
  • AIDS ( 19754311)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 29325848)
  • Body mass index ( 25673413)
  • Chronic back pain ( 30261039)
  • Chronotype ( 30696823)
  • Creatinine levels ( 29403010)
  • Depression ( 29700475)
  • Eye color ( 33692100)
  • Glomerular filtration rate ( 29403010)
  • Heart rate response to exercise ( 29769521)
  • Heart rate response to recovery post exercise ( 29769521)
  • Heel bone mineral density ( 30598549)
  • Height ( 28552196)
  • Hip circumference adjusted for BMI ( 34021172)
  • Inflammatory bowel disease ( 27569725)
  • Juvenile osteochondritis dissecans ( 26422391)
  • LDL peak particle diameter (total fat intake interaction) ( 26112879)
  • Mortality in sepsis ( 27639821)
  • Multisite chronic pain ( 33830993)
  • Non-obstructive azoospermia ( 22197933)
  • Normal facial asymmetry (angle of surface orientation score) ( 30631343)
  • Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • PR interval ( 29127183 30046033 32439900 20062060)
  • Response to antipsychotic treatment ( 20195266)
  • Response to statin therapy ( 20339536)
  • Resting heart rate ( 29769521 27798624)
  • Schizophrenia ( 29483656)
  • Systemic sclerosis ( 21779181)
  • Systolic blood pressure ( 30224653)
  • T wave morphology restitution during exercise ( 31607149)
  • T wave morphology restitution during exercise (MTAG) ( 31607149)
  • T wave morphology restitution during recovery from exercise ( 31607149)
  • T wave morphology restitution during recovery from exercise (MTAG) ( 31607149)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes 126 interacting genes: - ACY3 ADA AKT1 AR ATF2 C1QA C5orf24 CBS CCHCR1 CCNDBP1 CDCA8 CGGBP1 CHMP4B CLDN2 CREB1 CREBBP CTBP1 DDX39B DES DEUP1 DMC1 DNMT3A EDC3 ELK1 ESR1 ESR2 EXOSC8 FAM118B FKBP6 FLI1 GFAP GLUL GOLGA2 GRHL2 GRM8 GTF2I GTF2IRD1 HDAC3 HMBOX1 HMG20A HMG20B HMGXB4 HNRNPCL1 HNRNPUL1 HOMER1 HOOK1 HUWE1 IKZF1 IMPDH1 JUN KIFC3 LCE1E LCE2C LMNA LMNB1 MAPK8 MAPKAPK2 MBD1 MITF MLX MSX2 MX1 MX2 NAV2 NME7 NR3C1 PAICS PARK7 PAXIP1 PGR PHC1 PIAS1 PIAS4 PLAG1 PLAGL1 PML PRKAB2 PRKRA PRPH RFX2 RUFY1 RUNX1T1 SEC23A SIAH1 SIAH2 SMAD3 SMAD4 SNAI2 SNIP1 SOX5 SPATC1L SPINDOC SREBF2 STAT4 SUMO1 SUMO1P1 SUMO2 SUMO3 SYN3 TCF4 TH TICAM2 TP53 TRAF2 TRAF3 TRAF5 TRIM23 TRIM27 TRIM50 TRIM55 TRIM63 TSR2 TXLNA UBASH3B UBE2I UBE2L3 UBQLN1 ZBED1 ZBTB16 ZBTB8A ZC3H10 ZFP42 ZNF319 ZNF451 ZNRD2 41 interacting genes: ABCC9 APP ARID5A BCAT1 BIRC7 C2CD5 CAMK2A CBX8 CDC23 CDC25A CDK6 CRX FTH1 FXR1 IRAG2 KAT5 KIFC3 LMO1 LMO2 MAGED1 MED27 MORN3 MSX2 PIAS2 PRR20A RNF4 RPS2 SMAD1 SMAD5 SMAD7 SOX6 SUMO1P1 TENT5B TEX11 TLE5 TRAF2 TTC1 UBE2I UQCRFS1 ZBTB26 ZNF581
Entrez ID 9063 6660
HPRD ID 06944 18086
Ensembl ID ENSG00000078043 ENSG00000134532
Uniprot IDs A0A024RC49 O75928 Q2TA77 A0A024RB06 F5H0I3 P35711 T2CYZ2 T2CZM2
PDB IDs 2ASQ 4FO9
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?