CCNE1 and ARHGEF5

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CCNE1

ARHGEF5

Description cyclin E1 Rho guanine nucleotide exchange factor 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 23535729)
  • Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes 71 interacting genes: AKT1 AR ARHGEF5 ARID4A ARIH1 ARNT AURKA BRCA2 BTRC CABLES1 CALM1 CCND2 CCT4 CDC25A CDC6 CDK1 CDK2 CDK3 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C COIL CUL3 FBXW7 FGFR4 FOXM1 FZR1 GLIS2 GMNC GRM1 GSK3B H1-0 H1-1 H1-5 HERC5 KAT2A LATS2 MARCKS MCM3 MEGF8 MRE11 MYBL2 MYC NBN NF2 PIN1 POLD1 PRC1 PRKAR1A PTPA RASSF1 RB1 RBL1 RBL2 REL RHOBTB3 RRN3 SKP2 SMARCA4 SMARCC1 SMARCD3 SPOP STK11 TERT TP73 TSC1 UBTF 29 interacting genes: APP ATP13A1 CALCOCO2 CCNE1 CHPF COG6 EFHC2 EPM2AIP1 FKBP8 HSF2BP HSPBAP1 LMO2 LRATD1 MB21D2 MID2 NR4A1 PICK1 PLCG1 PLEKHG4 POLR1C RHOA SEPHS2 SLAIN1 SLU7 TBC1D13 TCF4 TRIM27 TRIM54 ZRANB1
Entrez ID 898 7984
HPRD ID 00455 02932
Ensembl ID ENSG00000105173 ENSG00000050327
Uniprot IDs A0A0G3DHS8 P24864 V5W5X2 Q12774
PDB IDs 1W98 5L2W
Enriched GO Terms of Interacting Partners?
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