ASAP2 and ARF5

Number of citations of the paper that reports this interaction (PubMedID 10749932)
36

Data Source:
HPRD (in vivo)

		ASAP2	ARF5
Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	ADP ribosylation factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Golgi Cisterna Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Positive Regulation Of GTPase Activity	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic obstructive pulmonary disease ( 30804561) Chronic widespread musculoskeletal pain ( 33331911) Pulse pressure ( 27841878 30578418) Urate levels ( 31578528)	Type 2 diabetes ( 23532257)
Interacting Genes		15 interacting genes: APC ARF1 ARF5 ARF6 BIN1 GRB2 ITSN1 PACSIN3 PTK2B PXN RAN REPS2 RRM2 SH3KBP1 THSD7A	16 interacting genes: AASS ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DTX3 ERBB2 GGA1 GORAB IKBKG MPHOSPH9 PALS2 PIP5K1A RAB11FIP3
Entrez ID		8853	381
HPRD ID		04820	00055
Ensembl ID		ENSG00000151693	ENSG00000004059
Uniprot IDs		O43150	A4D0Z3 P84085
PDB IDs			2B6H
Enriched GO Terms of Interacting Partners?
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