ARF5 and AASS

		ARF5	AASS
Description		ADP ribosylation factor 5	aminoadipate-semialdehyde synthase
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Transcription Corepressor Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle-mediated Transport	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid Negative Regulation Of Histone Methylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Lysine catabolism
Drugs			Glutamic acid NADH NADPH L-Saccharopine
Diseases
GWAS		Type 2 diabetes ( 23532257)	Opioid dependence (time to event) ( 34124712)
Interacting Genes		16 interacting genes: AASS ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DTX3 ERBB2 GGA1 GORAB IKBKG MPHOSPH9 PALS2 PIP5K1A RAB11FIP3	7 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 OGT PTPRZ1 WASL
Entrez ID		381	10157
HPRD ID		00055	05489
Ensembl ID		ENSG00000004059	ENSG00000008311
Uniprot IDs		A4D0Z3 P84085	A4D0W4 Q9UDR5
PDB IDs		2B6H	5L76 5L78 5O1N 5O1O 5O1P
Enriched GO Terms of Interacting Partners?
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