SYNGAP1 and GRIN2B

  • Number of citations of the paper that reports this interaction (PubMedID 9620694)
  • 163
  • Data Source:
  • HPRD (in vivo)

SYNGAP1

GRIN2B

Description synaptic Ras GTPase activating protein 1 glutamate ionotropic receptor NMDA type subunit 2B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Late-onset Alzheimer's disease ( 27770636)
  • Schizophrenia ( 30285260)
  • Adventurousness ( 30643258)
  • Aging (time to event) ( 21782286)
  • Alzheimer's disease in hypertension ( 31055733)
  • Anxiety ( 33859377)
  • Brain structure (temporal lobe volume) ( 20197096)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cognitive performance ( 19734545)
  • Dietary fat liking ( 32516399)
  • Egg allergy (parent-of-origin effect) ( 29489655)
  • General risk tolerance (MTAG) ( 30643258)
  • Height ( 31562340)
  • Immune reponse to smallpox (secreted IL-2) ( 22610502)
  • Keratoconus ( 33649486)
  • Major depressive disorder ( 23377640)
  • Opioid dependence (time to event) ( 34124712)
  • Ovarian reserve ( 22116950)
  • Refractive error ( 32231278)
  • Response to selective serotonin reuptake inhibitors in depression ( 30034349)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systolic blood pressure ( 30224653)
  • Total ventricular volume ( 21116278)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 29 interacting genes: CAMK2A DLG3 DLG4 DLGAP4 EFHC1 GRIN1 GRIN2B GRIN2D GUCD1 HSF2BP KDR MGAT5B MID2 MKRN3 MPDZ NCK2 NTAQ1 OSTF1 PDGFRB SHANK3 SPAG8 SUOX TLX3 TRIM27 TRIP6 TSSK3 ULK1 ULK2 VENTX 46 interacting genes: ACTN2 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CAMK2D CAMK2G CAMK2N1 CAPN1 CSNK2A1 CSNK2A2 CSNK2B DLG1 DLG2 DLG3 DLG4 EGFR EPHB2 ERBIN EXOC4 EXOC7 FYN GRIN1 GRIN2A GRIN3A IL16 LIN7A LIN7B MAGI3 MIB2 PATJ PIK3CA PLCG1 PRKCA PRKCB PRKCG PRKN PTPN11 RACK1 RASGRF1 SPTAN1 SRC SYNGAP1 TANC1
Entrez ID 8831 2904
HPRD ID 16018 00697
Ensembl ID ENSG00000197283 ENSG00000273079
Uniprot IDs A0A1U9X8L0 B7ZCA0 Q96PV0 Q13224
PDB IDs 1S11 1S2S 2IPV 5EWJ 5EWL 5EWM 6XBP 6XBX 6XDL 6XDU 6XOE 7KL0 7KL1 7KL2 7KL4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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