CBR1 and CHAF1B

		CBR1	CHAF1B
Description		carbonyl reductase 1	chromatin assembly factor 1 subunit B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome Extracellular Vesicle	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex
	Molecular Function	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding
	Biological Process	Xenobiotic Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)	Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		13 interacting genes: AGTR1 CHAF1B ERBB2 ERCC8 HRK HTR2B JAK1 LZTS1 OGT PRKAR2B PTPRF UBC VHL	15 interacting genes: APP ASF1A ASF1B CBR1 CDK1 CDK2 CHAF1A H3-4 H3C6 MAL2 PGM1 PRELP RBBP4 SETD4 SUMO2
Entrez ID		873	8208
HPRD ID		00267	03147
Ensembl ID		ENSG00000159228	ENSG00000159259
Uniprot IDs		A0A384NL53 P16152	Q13112
PDB IDs		1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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