CBR1

Description		carbonyl reductase 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity
	Biological Process	Xenobiotic Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)
Interacting Genes		13 interacting genes: AGTR1 CHAF1B ERBB2 ERCC8 HRK HTR2B JAK1 LZTS1 OGT PRKAR2B PTPRF UBC VHL
Entrez ID		873
HPRD ID		00267
Ensembl ID		ENSG00000159228
Uniprot IDs		A0A384NL53 P16152
PDB IDs		1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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