CHAF1B and SETD4

		CHAF1B	SETD4
Description		chromatin assembly factor 1 subunit B	SET domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Nucleus Cytosol
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Protein-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific) Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Inflammatory Response Peptidyl-lysine Trimethylation Peptidyl-lysine Monomethylation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Histone H4-K20 Trimethylation Histone H3-K4 Dimethylation Positive Regulation Of Inflammatory Response Regulation Of Cell Proliferation In Bone Marrow Histone H3-K4 Monomethylation
Pathways
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)	Asthma (adult onset) ( 31036433) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Obesity-related traits ( 23251661)
Interacting Genes		15 interacting genes: APP ASF1A ASF1B CBR1 CDK1 CDK2 CHAF1A H3-4 H3C6 MAL2 PGM1 PRELP RBBP4 SETD4 SUMO2	3 interacting genes: CHAF1B CIAO2A MORC3
Entrez ID		8208	54093
HPRD ID		03147	10743
Ensembl ID		ENSG00000159259	ENSG00000185917
Uniprot IDs		Q13112	A8MTS1 Q9NVD3
PDB IDs
Enriched GO Terms of Interacting Partners?
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