SKAP1 and FAM102A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SKAP1	FAM102A
Description		src kinase associated phosphoprotein 1	family with sequence similarity 102 member A
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction T Cell Receptor Complex Plasma Membrane Raft
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding SH2 Domain Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Adaptive Immune Response Positive Regulation Of Adaptive Immune Response Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane Positive Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Epithelial ovarian cancer ( 25581431) Food allergy ( 29030101) Generalized epilepsy ( 22949513) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Keratoconus ( 33649486) Lean body mass ( 28552196) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Ovarian cancer ( 20852632) Peanut allergy ( 29030101) Pulse pressure ( 30578418) White blood cell count ( 32888494)	Albumin-globulin ratio ( 29403010) Body mass index ( 26426971) Glaucoma (primary angle closure) ( 27064256) Monocyte count ( 29403010) Urate levels ( 31578528)
Interacting Genes		15 interacting genes: APP BLCAP DYNLL2 ELOC FAM102A FYB1 FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC TBKBP1	8 interacting genes: BCAR1 CYSRT1 ENKD1 NEDD9 PFDN5 SH3GL1 SKAP1 SKAP2
Entrez ID		8631	399665
HPRD ID		05396	13262
Ensembl ID		ENSG00000141293	ENSG00000167106
Uniprot IDs		Q86WV1 V9HW03	Q5T9C2
PDB IDs		1U5D
Enriched GO Terms of Interacting Partners?
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