SKAP1 and TBKBP1

		SKAP1	TBKBP1
Description		src kinase associated phosphoprotein 1	TBK1 binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction T Cell Receptor Complex Plasma Membrane Raft	Cytoplasm
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding SH2 Domain Binding Protein-containing Complex Binding	Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Adaptive Immune Response Positive Regulation Of Adaptive Immune Response Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane Positive Regulation Of Leukocyte Cell-cell Adhesion	I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Epithelial ovarian cancer ( 25581431) Food allergy ( 29030101) Generalized epilepsy ( 22949513) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Keratoconus ( 33649486) Lean body mass ( 28552196) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Ovarian cancer ( 20852632) Peanut allergy ( 29030101) Pulse pressure ( 30578418) White blood cell count ( 32888494)	Ankylosing spondylitis ( 23749187 21743469) Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Human herpesÂ virusÂ 7 U14Â antibodyÂ levels ( 33204752) Mean corpuscular hemoglobin ( 32888494) Multiple sclerosis ( 22190364) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		15 interacting genes: APP BLCAP DYNLL2 ELOC FAM102A FYB1 FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC TBKBP1	6 interacting genes: AGO2 APBA3 CALCOCO2 CBX1 RB1CC1 SKAP1
Entrez ID		8631	9755
HPRD ID		05396	12239
Ensembl ID		ENSG00000141293	ENSG00000198933
Uniprot IDs		Q86WV1 V9HW03	A7MCY6
PDB IDs		1U5D
Enriched GO Terms of Interacting Partners?
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