FAM102A and SKAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		FAM102A	SKAP1
Description		family with sequence similarity 102 member A	src kinase associated phosphoprotein 1
Image		No pdb structure
GO Annotations	Cellular Component		Immunological Synapse Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction T Cell Receptor Complex Plasma Membrane Raft
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Protein Phosphatase Binding SH2 Domain Binding Protein-containing Complex Binding
	Biological Process		Positive Regulation Of Cell-matrix Adhesion Adaptive Immune Response Positive Regulation Of Adaptive Immune Response Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane Positive Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Body mass index ( 26426971) Glaucoma (primary angle closure) ( 27064256) Monocyte count ( 29403010) Urate levels ( 31578528)	Body mass index ( 28892062 25673413) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) Epithelial ovarian cancer ( 25581431) Food allergy ( 29030101) Generalized epilepsy ( 22949513) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Keratoconus ( 33649486) Lean body mass ( 28552196) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Ovarian cancer ( 20852632) Peanut allergy ( 29030101) Pulse pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		8 interacting genes: BCAR1 CYSRT1 ENKD1 NEDD9 PFDN5 SH3GL1 SKAP1 SKAP2	15 interacting genes: APP BLCAP DYNLL2 ELOC FAM102A FYB1 FYN GRB2 LCK LYN PRAM1 PTPRC SH2D4A SRC TBKBP1
Entrez ID		399665	8631
HPRD ID		13262	05396
Ensembl ID		ENSG00000167106	ENSG00000141293
Uniprot IDs		Q5T9C2	Q86WV1 V9HW03
PDB IDs			1U5D
Enriched GO Terms of Interacting Partners?
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