PDXK and GET1

		PDXK	GET1
Description		pyridoxal kinase	guided entry of tail-anchored proteins factor 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytosol Secretory Granule Lumen Specific Granule Lumen Extracellular Exosome	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane GET Complex
	Molecular Function	Magnesium Ion Binding ATP Binding Zinc Ion Binding Pyridoxal Kinase Activity Pyridoxal Phosphate Binding Potassium Ion Binding Sodium Ion Binding Lithium Ion Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Pyridoxal 5'-phosphate Salvage Phosphorylation	Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Neutrophil degranulation Vitamins B6 activation to pyridoxal phosphate	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Pyridoxal Pyridoxine Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL (2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol
Diseases
GWAS		Blood protein levels ( 30072576) Refractive error ( 32231278) Systolic blood pressure change trajectory ( 27980656)
Interacting Genes		4 interacting genes: BARD1 GET1 RIPK1 YWHAQ	34 interacting genes: ABHD5 APOA2 APOL2 AQP1 BOC CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 GATD3 HMOX2 HTATIP2 ORMDL3 PDXK PLPP4 PTPN9 RASGRP3 RTP2 SCN3A SERP2 SLC35E3 SLC4A2 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42 TRAPPC10
Entrez ID		8566	7485
HPRD ID		01526	04224
Ensembl ID		ENSG00000160209	ENSG00000182093
Uniprot IDs		F2Z2Y4 O00764 V9HWC3	O00258
PDB IDs		2AJP 2F7K 2YXT 2YXU 3FHX 3FHY 3KEU 4EN4 4EOH	6SO5
Enriched GO Terms of Interacting Partners?
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