GET1 and CLCN7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GET1	CLCN7
Description		guided entry of tail-anchored proteins factor 1	chloride voltage-gated channel 7
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GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane GET Complex	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane	Response To PH Chloride Transmembrane Transport
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Stimuli-sensing channels
Drugs
Diseases
GWAS			Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)
Interacting Genes		34 interacting genes: ABHD5 APOA2 APOL2 AQP1 BOC CAMLG CCL4L2 CD302 CD53 CLCN7 COMT COX20 ERG28 GATD3 HMOX2 HTATIP2 ORMDL3 PDXK PLPP4 PTPN9 RASGRP3 RTP2 SCN3A SERP2 SLC35E3 SLC4A2 SLC7A1 SPTSSA STX2 TECR TFRC TM4SF19 TMEM42 TRAPPC10	16 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B
Entrez ID		7485	1186
HPRD ID		04224	04103
Ensembl ID		ENSG00000182093	ENSG00000103249
Uniprot IDs		O00258	P51798
PDB IDs		6SO5	7BXU 7CQ5 7CQ6 7CQ7 7JM7
Enriched GO Terms of Interacting Partners?
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